Bills vs. 49ers Injury Update: San Francisco Faces Challenges Ahead of Sunday Clash
The Buffalo Bills, riding a six-game winning streak, appear to be in better health as they prepare to host the injury-plagued San Francisco 49ers on Sunday Night Football. While Buffalo (9-2) maintains Super Bowl aspirations, the 49ers (5-6), last year’s NFC champions, are fighting to stay in playoff contention after back-to-back losses.
Coming off a bye week, the Bills are poised to benefit from returning players. Key contributors like wide receiver Keon Coleman, tight end Dalton Kincaid, and offensive tackle Spencer Brown, who missed their Week 11 victory over the Kansas City Chiefs, are making progress. Linebacker Matt Milano, sidelined since training camp with a torn biceps, has begun practicing after his 21-day injured reserve window was opened. Defensive tackle DeWayne Carter is also eligible to return.
Meanwhile, the 49ers continue to battle significant injuries. Missing four Pro Bowlers—quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa, and cornerback Charvarius Ward—they suffered a lopsided 38-10 loss to Green Bay in Week 12. Purdy’s status remains uncertain due to a lingering shoulder injury, and if he is unavailable, Brandon Allen (2-8 as a starter) will step in again. Despite some light throwing on Monday, Purdy’s ability to play hinges on his recovery throughout the week.
San Francisco coach Kyle Shanahan expressed hope for Purdy’s return but emphasized caution. Additionally, linebacker Drew Greenlaw’s practice window is set to open, though offensive guard Jon Feliciano remains on injured reserve for the season.
Key Updates for Buffalo Bills
- Keon Coleman (WR): Coleman has missed two games with a wrist injury sustained in Week 9 but avoided injured reserve.
- Dalton Kincaid (TE): Sidelined in Week 11 due to a knee injury, Kincaid has been progressing after an earlier setback.
- Spencer Brown (OT): Recovering from a right ankle injury sustained in Week 10.
- Matt Milano (LB): Practicing again after a long IR stint but remains day-to-day.
49ers’ Outlook
San Francisco’s injury report highlights their uphill battle, with potential absences across key positions. NFL rules require teams to update practice participation daily, with official game statuses due by Friday evening.
This matchup pits the Bills’ offensive momentum against the 49ers’ resilience as both teams navigate their respective injury challenges.